Images from the EPL matches played on Sunday
Ahead of their high-profile clash on Saturday, check out the five standout clashes between Arsenal and Chelsea.
Arsenal conceded five goals for the first time at their Emirates Stadium as they suffered their worst home defeat for 19 years.
Arsenal climbed into the top four with a laboured 2-1 win over Leicester City.
A second-half penalty by Mikel Arteta earned Arsenal a 1-0 victory at Wigan Athletic on Saturday to move the Gunners up to third place in the Premier League.
Arsenal have left six first-team regulars in London ahead of their final Champions League group stage match against Olympiakos Piraeus in a bid to avoid fatigue following the home defeat to Swansea City.
Arsenal handed the Premier League initiative back to leaders Manchester United on Saturday with a limp performance in a goalless home draw against a Sunderland side who had lost their previous four games.
Theo Walcott's double fired Arsenal back to the top of the Premier League as the Gunners got their title challenge back on track with a 3-1 victory at West Ham United on Thursday.
Arsenal's faint hopes of winning the Premier League title were finally killed off when Wigan Athletic scored three goals in the last 10 minutes to snatch a dramatic 3-2 victory on Sunday.
Champions Manchester United reduced Arsenal's lead to three points when they thrashed Newcastle United 5-1.
Birmingham drew 2-2 with Arsenal after James McFadden equalised with a late penalty in the EPL tie.
Arsenal demolished Slavia Prague 7-0 in Champions League Group H on Wednesday with one of the most brilliant displays of attacking football since the Champions League began 15 years ago.
Arsenal teetered on the brink of elimination before coming from behind to win 2-1 at Udinese and qualify for the Champions League for the 14th season in a row on Wednesday.
rsenal boss Arsene Wenger and striker Olivier Giroud were named the Premier League manager and player of the month.
Chelsea and Arsenal notched impressive 6-0 victories on Saturday as the champions destroyed Wigan Athletic and Arsene Wenger's team brought 10-man Blackpool crashing back to Premier League reality.
Arsenal's hopes of catching Manchester City for second place in the Premier League suffered a setback.
A clinical second-half display earned Arsenal a 3-0 win at Swansea City on Saturday and proved they are ready to mount a sustained Premier League title challenge.
Dutch striker Robin van Persie enjoyed an eventful return to his old club Arsenal for the first time when he scored and was booked as champions Manchester United held the Londoners to a 1-1 draw at the Emirates.
Arsenal climbed above Manchester United into second place in the Premier League with a 3-1 home win over Burnley on Saturday.
Free-scoring Arsenal replaced Chelsea as Premier League leaders as goals either side of halftime by Theo Walcott and Mesut Ozil helped them recover from a slow start to beat Stoke City 3-1 on Saturday.
Champions Liverpool are five points clear at the top of the Premier League after a 7-0 away hammering of Crystal Palace while Arsenal's troubles continued with a 2-1 defeat at second-placed Everton on Saturday.
Olivier Giroud scored the decisive spot kick as Arsenal beat Chelsea 4-1 in a penalty shootout to win the Community Shield at Wembley on Sunday.
France defender William Gallas scored two minutes from time to salvage a 1-1 draw for Arsenal against Dynamo Kiev in their Champions League tie on Wednesday.
Theo Walcott and Nicklas Bendtner made goalscoring returns from injury on Wednesday as Arsenal thrashed Newcastle United 4-0 away to reach the last eight of the League Cup.
Arsenal beat Brighton and Hove Albion 3-2 to reach the FA Cup fifth round.
Arsenal will not sell striker Olivier Giroud, midfielder Jack Wilshere and winger Theo Walcott in the January transfer window despite their lack of playing time at the Premier League club, manager Arsene Wenger has said.
Round up of the Champions League matches played on Wednesday.
FA Cup winners Arsenal beat champions Chelsea 1-0 in England's Community Shield season curtain-raiser at Wembley on Sunday to end a long wait for victory over their London rivals.
Arsenal ended their seven match winless run in the Premier League with a surprise 3-1 London derby victory over Chelsea at the Emirates Stadium on Saturday while Manchester United were held to a 2-2 draw at Leicester City.
Arsenal's hopes of qualifying for the Champions League for the 14th time in a row were in the balance after a 1-0 win at home to Udinese in the first leg of the playoffs on Tuesday.
Arsenal shoved Chelsea off the top of the table but Leicester City's Jamie Vardy, with a dazzling hat-trick, was the man of the moment on Saturday as the struggling Premier League champions blew aside Manchester City 4-2.
Holders Arsenal's long unbeaten run in the FA Cup continued but they were frustrated by stubborn Championship leaders Hull City on Saturday, drawing 0-0 in a dreary fifth-round tie at the Emirates Stadium.
Arsenal scored three goals in a seven-minute burst after halftime against visitors Aston Villa, including two penalties from Robin van Persie, as they staged a dramatic comeback to win 3-2 and reach the FA Cup fifth round on Sunday.
Barcelona will put Manchester City to the sword if they commit the same kind of errors as they did in their Champions League encounter last month, coach Luis Enrique said.
A fixture billed as a pre-Christmas cracker was more 'In the Bleak Midwinter' than 'Jingle Bell Rock' as Arsenal's hopes of regaining top spot in the Premier League fizzled out in a turgid 0-0 draw with Chelsea.
Arsenal are still in contention for the English Premier League title and it is too soon to say that leaders Chelsea can go through the season undefeated, manager Arsene Wenger said.
Manchester United beat Porto 1-0 while Arsenal trounced Villarreal 3-0 in second leg quarter-final matches in the Champions League to make the grade.
A full-strength Arsenal added another piece of silverware to their recent FA Cup success by beating Everton 3-1 in the final of the Premier League's Asia Trophy on Saturday.
Kevin De Bruyne, Kelechi Iheanacho, Raheem Sterling and Ilkay Gundogan gave Man City a 4-0 win over Bournemouth before Nolito was sent off.
A controversial last-gasp goal deflected into the net off Laurent Koscielny's hand from a close-range shot by Alex Oxlade-Chamberlain gave Arsenal a lucky 1-0 victory at Burnley on Sunday as manager Arsene Wenger marked his 20th anniversary at the club.